Retatrutide – Research Peptide (GLP-1 / GLP-3)
Retatrutide – Research Peptide (GLP-1 / GLP-3)
Product Overview
8 West Bio is a U.S.-based Retatrutide supplier focused on research customers. Orders are fulfilled from U.S. inventory with batch documentation available directly on this page. Purchase through this listing provides access to current lots, including single vials and 10-pack options for ongoing studies.
What Is Retatrutide?
Retatrutide is a synthetic triple-agonist peptide studied in metabolic and receptor-signaling research models for simultaneous activity at:
- GLP-1 receptor — incretin-pathway signaling models
- GIP receptor — complementary incretin signaling research
- Glucagon receptor — energy-balance and lipid signaling models
Mechanistic Overview
- GLP-1 axis: receptor-mediated signaling models and glucose dynamics research
- GIP axis: glucose-dependent signaling pathways and incretin synergy research
- Glucagon axis: lipid mobilization and energy-expenditure pathway modeling
Research Evidence Snapshot
Published preclinical and Phase 2 literature describes metabolic endpoints associated with triple-agonist peptides compared to single- and dual-agonist incretin approaches. Researchers should review primary sources for protocol design, model selection, and methodological details applicable to their work.
Retatrutide vs Tirzepatide vs Semaglutide
| Feature | Retatrutide | Tirzepatide | Semaglutide |
|---|---|---|---|
| Agonism | Triple: GLP-1, GIP, Glucagon | Dual: GLP-1, GIP | Single: GLP-1 |
| Research Focus | Combined receptor-pathway signaling models | Incretin pathway research | GLP-1 axis signaling models |
| Design Notes | Includes glucagon-axis activity in research models | Well-characterized dual incretin profile | Single-pathway incretin agent |
Product Specifications
- Name: Retatrutide
- Synonyms: LY3437943
- Purity: ≥99% (independent third-party HPLC/MS)
- Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
- Molecular Weight: ~4,731.33 g/mol
- Intended use: In-vitro/ex-vivo research only
Storage & Stability
- Unreconstituted: Store dry and light-protected
- After reconstitution: 2–8 °C; aliquot to reduce freeze-thaw cycles
- Shelf life: 4 years
Regulatory & Safety
All products are supplied for laboratory and scientific research. Products are not approved for human or veterinary use. End users are responsible for compliance with institutional requirements and applicable laws. Purchase constitutes acceptance of these terms.
Retatrutide FAQ
- What vial sizes are available?
- Retatrutide research vials are available in 10 mg, 20 mg and 30 mg fills.
- Is this fulfilled from within the USA?
- Yes. Orders are fulfilled from U.S. inventory with appropriate packing for the shipment route.
- Do you provide a Certificate of Analysis (COA)?
- Yes. A current, batch-specific COA is posted on this product page for verification.